Liang Shu-Yi, Chu Hong-Liang, Guo Xi-Ling, Wang Wei, Chen Hong-Na, Zhang Yu-Fu, Chen Yin, Wu Tao, Bao Chang-Jun, Zhou Ming-Hao
Jiangsu Provincial Center for Disease Control and Prevention, No. 172 Jiangsu Road, Nanjing, People's Republic of China.
Jiangsu Institute of Parasitic Diseases, No. 117 Yangxiang, Meiyuan, Wuxi, People's Republic of China.
Infect Dis Poverty. 2017 Jun 1;6(1):78. doi: 10.1186/s40249-017-0282-6.
Severe fever with thrombocytopenia syndrome (SFTS) is a newly identified emerging infectious disease, which is caused by a novel bunyavirus (termed SFTSV) in Asia. Although mosquitoes have not been identified as the primary vectors, as revealed by epidemiological surveys, their role in transmitting this SFTSV as a suspicious vector has not been validated.
In this study, we conducted experimental infections of mosquitoes with SFTSV to examine the role of mosquitoes in the transmission of the virus. We did not detect viral replication in Culex pipiens pallens, Aedes aegyptis and Anopheles sinensis as revealed by qRT-PCR assay. In addition, we failed to isolate SFTSV from the Vero cells cultured with suspensions of SFTSV-infected mosquitoes.
The results of the present study demonstrate little possibility that mosquitoes act as vectors for the emerging pathogen SFTSV.
发热伴血小板减少综合征（SFTS）是一种新发现的新发传染病，由亚洲一种新型布尼亚病毒（称为SFTS病毒）引起。尽管流行病学调查显示蚊子尚未被确定为主要传播媒介，但它们作为可疑传播媒介传播这种SFTS病毒的作用尚未得到证实。
在本研究中，我们用SFTS病毒对蚊子进行了实验性感染，以研究蚊子在病毒传播中的作用。通过qRT-PCR检测，我们未在淡色库蚊、埃及伊蚊和中华按蚊中检测到病毒复制。此外，我们未能从用感染SFTS病毒的蚊子悬液培养的Vero细胞中分离出SFTS病毒。
本研究结果表明，蚊子作为新兴病原体SFTS病毒传播媒介的可能性很小。
