FAM13A, A Fatty Acid Oxidation Switch in Mitochondria. Friend or Foe in Chronic Obstructive Pulmonary Disease Pathogenesis?
作者信息
Hawkins Gregory A, Mora Ana L
机构信息
1 Center for Genomics and Personalized Medicine Research Wake Forest School of Medicine Winston-Salem, North Carolina.
2 Division of Pulmonary, Allergy, and Critical Care Medicine Vascular Medicine Institute University of Pittsburgh Pittsburgh, Pennsylvania.
出版信息
Am J Respir Cell Mol Biol. 2017 Jun;56(6):689-691. doi: 10.1165/rcmb.2017-0080ED.
Abstract
摘要
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本文引用的文献
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2
A Chronic Obstructive Pulmonary Disease Susceptibility Gene, FAM13A, Regulates Protein Stability of β-Catenin.一种慢性阻塞性肺疾病易感基因FAM13A，调控β-连环蛋白的蛋白质稳定性。
Am J Respir Crit Care Med. 2016 Jul 15;194(2):185-97. doi: 10.1164/rccm.201505-0999OC.
3
Mitochondrial iron chelation ameliorates cigarette smoke-induced bronchitis and emphysema in mice.线粒体铁螯合改善香烟烟雾诱导的小鼠支气管炎和肺气肿。
Nat Med. 2016 Feb;22(2):163-74. doi: 10.1038/nm.4021. Epub 2016 Jan 11.
4
A Genome-Wide Association Study of Emphysema and Airway Quantitative Imaging Phenotypes.一项关于肺气肿和气道定量成像表型的全基因组关联研究。
Am J Respir Crit Care Med. 2015 Sep 1;192(5):559-69. doi: 10.1164/rccm.201501-0148OC.
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Oxidative stress-induced mitochondrial dysfunction drives inflammation and airway smooth muscle remodeling in patients with chronic obstructive pulmonary disease.氧化应激诱导的线粒体功能障碍在慢性阻塞性肺疾病患者中驱动炎症和气道平滑肌重塑。
J Allergy Clin Immunol. 2015 Sep;136(3):769-80. doi: 10.1016/j.jaci.2015.01.046. Epub 2015 Mar 29.
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