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不明原因的脓毒性盆腔血栓性静脉炎:一个始终具有威胁性的病症。

Septic pelvic thrombophlebitis of unknown origin: an ever threatening entity.

作者信息

Roepke Roberta Muriel Longo, de Campos Fernando Peixoto Ferraz, Lovisolo Silvana Maria, Santos Eduardo Henrique Sena

机构信息

Department of Internal Medicine - Hospital das Clínicas - Faculdade de Medicina - Universidade de São Paulo, São Paulo/SP - Brazil.

Department of Internal Medicine - Hospital Universitário - Universidade de São Paulo, São Paulo/SP - Brazil.

出版信息

Autops Case Rep. 2014 Sep 30;4(3):39-46. doi: 10.4322/acr.2014.027. eCollection 2014 Jul-Sep.

Abstract

Septic pelvic thrombophlebitis (SPT) is a rare and severe entity, which may occur after abortion, delivery, gynecological diseases, or surgeries. Diagnosis is challenging when no risk factor is clearly present, since clinically, symptoms are non-specific. Nowadays, with the aid of imaging methods, diagnosis has become more achievable, but the treatment still bears some uncertainties. The authors present a fatal case of SPT in a young woman who sought medical care already presenting signs of septic shock, referring fever and non-characteristic abdominal pain. The patient evolved rapidly to multiple organ failure and respiratory distress, which was also due to septic pulmonary embolism. The autopsy confirmed the computed tomographic findings of a right ovarian vein septic thrombophlebitis and multiple septic pulmonary embolization foci. The patient did not present any of the recognized risk factors; neither did she present signs of pelvic inflammatory disease on admission or at autopsy. However, an intrauterine device was present. The authors call attention to this entity in the differential diagnosis of a woman with fever and abdominal pain, as well as for an empiric broad-spectrum antibiotic regimen in these cases.

摘要

脓毒性盆腔血栓性静脉炎(SPT)是一种罕见且严重的病症,可发生于流产、分娩、妇科疾病或手术后。当无明确的危险因素时,诊断具有挑战性,因为临床上症状不具有特异性。如今,借助影像学方法,诊断变得更可行,但治疗仍存在一些不确定性。作者报告了一例年轻女性SPT致死病例,该患者就医时已出现脓毒性休克迹象,表现为发热和非特异性腹痛。患者迅速发展为多器官功能衰竭和呼吸窘迫,这也是由脓毒性肺栓塞所致。尸检证实了计算机断层扫描结果,即右卵巢静脉脓毒性血栓性静脉炎和多个脓毒性肺栓塞灶。该患者未出现任何公认的危险因素;入院时及尸检时均未表现出盆腔炎迹象。然而,患者体内有宫内节育器。作者提醒在对发热和腹痛女性进行鉴别诊断时要注意这一病症,以及在这些病例中采用经验性广谱抗生素治疗方案。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4970/5444397/8dbccd328590/autopsy-04-03039-g01.jpg

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