Pleet Julia L, Taboada Sofia, Rishi Arvind, Milman Perry J, Trindade Arvind J
Department of Medicine, Division of Gastroenterology, Hofstra Northwell School of Medicine, Long Island Jewish Medical Center, New Hyde Park, New York, United States.
Department of Pathology, Hofstra Northwell School of Medicine, Long Island Jewish Medical Center, New Hyde Park, New York, United States.
Endosc Int Open. 2017 Jun;5(6):E484-E488. doi: 10.1055/s-0043-106579. Epub 2017 May 31.
Lymphocytic esophagitis (LyE) is a form of chronic esophagitis characterized by edema and lymphocytic infiltration of the epithelial peripapillary fields, without eosinophils. Its significance is unclear, as it was previously thought to have little clinical impact. More recent literature, however, describes a paradigm shift suggesting a distinct entity. We report on 3 patients with dysphagia who were found to have esophageal rings on endoscopy. Histology was consistent with LyE. Additional features reported in this cohort included an esophageal web, esophageal pseudodiverticula and esophageal erythema. We also report a current literature review of the topic. The literature review reported here includes another 37 patients with LyE and rings, for a total of 40 patients. Patients with LyE may present with esophageal rings and other findings. LyE should be considered in the differential diagnosis of esophageal rings.
淋巴细胞性食管炎(LyE)是一种慢性食管炎,其特征为上皮乳头周围区域水肿和淋巴细胞浸润,无嗜酸性粒细胞。其意义尚不清楚,因为以前认为它对临床影响很小。然而,最近的文献描述了一种范式转变,表明它是一种独特的疾病实体。我们报告了3例吞咽困难患者,在内镜检查中发现有食管环。组织学与淋巴细胞性食管炎一致。该队列中报告的其他特征包括食管蹼、食管假性憩室和食管红斑。我们还报告了该主题的当前文献综述。此处报告的文献综述包括另外37例患有淋巴细胞性食管炎和食管环的患者,共计40例患者。淋巴细胞性食管炎患者可能表现为食管环及其他表现。在食管环的鉴别诊断中应考虑淋巴细胞性食管炎。