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重度肥胖青少年减重手术的长期结果:对950例至少随访3年患者的系统评价和荟萃分析

Long-Term Outcome of Bariatric Surgery in Morbidly Obese Adolescents: a Systematic Review and Meta-Analysis of 950 Patients with a Minimum of 3 years Follow-Up.

作者信息

Shoar Saeed, Mahmoudzadeh Habibollah, Naderan Mohammad, Bagheri-Hariri Shahram, Wong Catherine, Parizi Ahmad Shahabeddin, Shoar Nasrin

机构信息

Department of Medicine and Surgery, Tehran University of Medical Sciences, No17, Isar 2 Alley, Khandaee street, Kashan, Tehran, 8719757161, Iran.

Department of Surgery, Cancer Institute, Imam Khomeini Hospital Complex, Tehran University of Medical Sciences, Tehran, Iran.

出版信息

Obes Surg. 2017 Dec;27(12):3110-3117. doi: 10.1007/s11695-017-2738-y.

Abstract

BACKGROUND

Obesity in pediatric and adolescent population has reached a universal pandemic. This study aimed to summarize the literature on the longest available outcome of bariatric surgery in morbidly obese adolescents.

METHODS

A systematic review was conducted to pool available data on the longest available (>3 years) weight loss and comorbidity resolution outcome in adolescent bariatric surgery.

RESULTS

A total of 14 studies reporting the result of bariatric surgery after 3 years in 950 morbidly obese adolescents were included. Preoperative age and BMI ranged from 12 to 19 years and from 26 to 91 kg/m, respectively. Females were the predominant gender (72.8%). Laparoscopic roux-en-Y gastric bypass (n = 453) and adjustable gastric banding (n = 265) were the most common bariatric procedure performed. The number of patients at the latest follow-up was 677 (range from 2 to 23 years). On average, patients lost 13.3 kg/m of their BMI. Among comorbidities, only diabetes mellitus resolved or improved dramatically. Of 108 readmissions, 91 led to reoperation. There was a weight regain < 5 kg/m between 5 and 6 years of follow-up. Removal, exchange, or conversion of the previous band constituted the majority of the revisional procedures. Three deaths were reported. No long-term data was obtainable on nutritional deficiency or growth status of adolescents who underwent a bariatric procedure.

CONCLUSION

Although bariatric surgery is a safe and effective procedure in the treatment of adolescent morbid obesity, long-term data is scarce regarding its nutritional and developmental complication in this growing population of patients.

摘要

背景

儿童和青少年肥胖已成为全球性的流行病。本研究旨在总结关于病态肥胖青少年接受减肥手术后最长可获得的结局的文献。

方法

进行了一项系统综述,以汇总关于青少年减肥手术中最长可获得的(>3年)体重减轻和合并症缓解结局的可用数据。

结果

共纳入14项研究,报告了950例病态肥胖青少年在接受减肥手术后3年的结果。术前年龄和体重指数分别为12至19岁和26至91kg/m²。女性占主导性别(72.8%)。腹腔镜Roux-en-Y胃旁路术(n = 453)和可调节胃束带术(n = 265)是最常见的减肥手术。最新随访时的患者人数为677例(随访时间为2至23年)。平均而言,患者的体重指数降低了13.3kg/m²。在合并症中,只有糖尿病得到显著缓解或改善。在108例再次入院病例中,91例导致再次手术。在随访5至6年期间,体重反弹<5kg/m²。先前束带的移除、更换或转换构成了大多数翻修手术。报告了3例死亡。对于接受减肥手术的青少年的营养缺乏或生长状况,无法获得长期数据。

结论

尽管减肥手术是治疗青少年病态肥胖的一种安全有效的方法,但在这一不断增长的患者群体中,关于其营养和发育并发症的长期数据却很匮乏。

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