奎宁中毒的并发症。

Complications of quinine poisoning.

作者信息

Boland M E, Roper S M, Henry J A

出版信息

Lancet. 1985 Feb 16;1(8425):384-5. doi: 10.1016/s0140-6736(85)91398-4.

Abstract

Of 165 patients admitted to hospital with acute quinine poisoning 70 (42%) had visual symptoms. 19 were left with a permanent visual deficit, though none was left completely blind. 5 patients died. Bilateral stellate ganglion block was carried out on 34 patients with impaired visual acuity or blindness, but an improvement of symptoms was reported in only 4 cases. It is concluded that stellate ganglion blockade is not effective enough to justify its regular use in quinine-induced amblyopia. Quinine overdose can have serious consequences, and the drug should not be prescribed indiscriminately.

摘要

165名因急性奎宁中毒入院的患者中，70名（42%）出现视觉症状。19人遗留永久性视力缺陷，不过无人完全失明。5名患者死亡。对34名视力受损或失明患者实施了双侧星状神经节阻滞，但仅4例报告症状有所改善。得出的结论是，星状神经节阻滞效果不够显著，不足以证明其可常规用于奎宁所致弱视。奎宁过量会产生严重后果，该药不应随意开处方。