1997年至2002年向苏格兰毒物信息局报告的奎宁中毒事件：一个持续存在的问题。
Quinine intoxications reported to the Scottish Poisons Information Bureau 1997-2002: a continuing problem.
作者信息
Langford N J, Good A M, Laing W J, Bateman D N
机构信息
West Midlands Centre for Adverse Drug Reaction Reporting, City Hospital, Birmingham, UK.
出版信息
Br J Clin Pharmacol. 2003 Nov;56(5):576-8. doi: 10.1046/j.1365-2125.2003.01921.x.
Quinine is widely prescribed in the UK for night cramps. Its potential toxicity in overdose is well known. We have reviewed the Scottish experience of enquiries regarding quinine overdose to the poisons information service responsible for Scotland over a 6-year period. Between 1997 and 2002 there were 96 reports of suspected quinine toxicity from Scotland (population 5.2 million), 19 of which were in children. The largest quantities of drug ingested were in patients between the ages of 11 and 30. In comparison with older studies the pattern of quinine poisoning does not appear to have changed in the UK over 20 years, despite recognition that it is a toxic agent in overdose, and particularly in children.
在英国，奎宁被广泛用于治疗夜间抽筋。其过量使用时的潜在毒性是众所周知的。我们回顾了苏格兰在六年时间里向负责苏格兰地区的毒物信息服务机构咨询奎宁过量问题的情况。1997年至2002年间，苏格兰（人口520万）有96例疑似奎宁中毒报告，其中19例是儿童。摄入药物量最大的是11至30岁的患者。与早期研究相比，尽管人们认识到奎宁过量尤其是对儿童来说是一种有毒物质，但在英国，奎宁中毒的模式在20年里似乎并未改变。
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