播散性非结核分枝杆菌病是否会导致结核分枝杆菌 LAM 侧向流动检测结果假阳性？一项回顾性研究。
Does Disseminated Nontuberculous Mycobacterial Disease Cause False-Positive Determine TB-LAM Lateral Flow Assay Results? A Retrospective Review.
机构信息
Division of Infectious Diseases, Department of Internal Medicine, Helen Joseph Hospital, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa.
Division of Infectious Diseases, Johns Hopkins University School of Medicine, Baltimore, Maryland.
出版信息
Clin Infect Dis. 2017 Oct 1;65(7):1226-1228. doi: 10.1093/cid/cix513.
We retrospectively reviewed the Determine TB-LAM lateral flow assay (LF-LAM) results among human immunodeficiency virus-infected patients with disseminated nontuberculous mycobacterial (NTM) disease. LF-LAM was positive in 19 of 21 patients without evidence of tuberculosis (TB) coinfection. Although TB-NTM coinfection may have been underdiagnosed, our results suggest that disseminated NTM disease may cause false-positive LF-LAM results.
我们回顾性分析了人类免疫缺陷病毒（HIV）感染伴播散性非结核分枝杆菌（NTM）病患者中使用结核分枝杆菌 LAM 检测试剂盒（LF-LAM）的检测结果。21 例无结核（TB）合并感染证据的患者中，19 例 LF-LAM 阳性。尽管可能存在 TB-NTM 合并感染的漏诊，但我们的结果表明，播散性 NTM 病可能导致 LF-LAM 假阳性结果。
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