Häfele César Augusto, Freitas Matheus Pintanel, da Silva Marcelo Cozzensa, Rombaldi Airton José
Escola Superior de Educação Física, Universidade Federal de Pelotas, RS, Brazil; Programa de Pós-Graduação em Educação Física, Universidade Federal de Pelotas, RS, Brazil; Grupo de Estudos em Epidemiologia da Atividade Física, Universidade Federal de Pelotas, RS, Brazil; School of Physical Education, Federal University of Pelotas, Rua Luís de Camões, 625, 96055630 Pelotas, RS, Brazil.
Epilepsy Behav. 2017 Jul;72:28-34. doi: 10.1016/j.yebeh.2017.04.038. Epub 2017 May 30.
The aim of the study was to investigate the association of physical activity in three categories (inactive, insufficiently active and active) with health outcomes in people with epilepsy. The dependent variables and the instruments used in the study were: a) quality of life - measured by Quality of Life in Epilepsy-31 for adults and Quality of Life in Epilepsy for Adolescents, b) side effects of medication - measured by Adverse Events Profile, c) depression - measured by Neurological Disorders Depression Inventory for Epilepsy, and d) state and trait anxiety - measured by State-Trait Anxiety Inventory. Physical activity levels were analyzed using the International Physical Activity Questionnaire (IPAQ) for adults in the commuting and leisure domains and Physical Activity Questionnaire for Adolescents (PAQ-A). Simple and multiple linear regression was used in the statistical analysis. The cross-sectional study with one hundred and one individuals was conducted in Pelotas/RS, Brazil, at the Neurology Clinic of the Faculty of Medicine of the Federal University of Pelotas. In the crude analysis, physical activity was positively associated with quality of life (p<0.001) and negatively associated with depression (p=0.046), state of anxiety (p=0.014), trait of anxiety (p=0.015) and side effect of medication (p=0.01). In addition, physical activity levels explained 10% of the quality of life (R=0.10). In the adjusted analysis, physical activity remained associated with side effect of medication (p=0.014) and was not associated with trait anxiety (p=0.066). However, quality of life showed a positive linear trend (p=0.001) while depression (p=0.033) and anxiety state (p=0.004) showed a negative trend according to physical activity levels. Physical activity was associated with health outcomes, and can be a nonpharmacological treatment in people with epilepsy for improving health and life conditions.
本研究的目的是调查癫痫患者中三类身体活动水平（不活动、活动不足和活动充分）与健康结果之间的关联。本研究中使用的因变量和工具如下：a）生活质量——采用成人癫痫生活质量量表-31和青少年癫痫生活质量量表进行测量；b）药物副作用——采用不良事件量表进行测量；c）抑郁——采用癫痫神经障碍抑郁量表进行测量；d）状态焦虑和特质焦虑——采用状态-特质焦虑量表进行测量。使用国际体力活动问卷（IPAQ）对成年人通勤和休闲领域的身体活动水平进行分析，并使用青少年体力活动问卷（PAQ-A）。统计分析采用简单和多元线性回归。这项横断面研究共纳入了101名个体，研究在巴西佩洛塔斯/南里奥格兰德州联邦大学医学院神经科诊所开展。在粗分析中，身体活动与生活质量呈正相关（p<0.001），与抑郁（p=0.046）、焦虑状态（p=0.014）、特质焦虑（p=0.015）和药物副作用（p=0.01）呈负相关。此外，身体活动水平解释了生活质量的10%（R=0.10）。在调整分析中，身体活动仍与药物副作用相关（p=0.014），与特质焦虑无关（p=0.066）。然而根据身体活动水平，生活质量呈正线性趋势（p=0.001），而抑郁（p=0.033）和焦虑状态（p=0.004）呈负趋势。身体活动与健康结果相关，并且可以作为癫痫患者改善健康和生活状况的一种非药物治疗方法。
