Hamidi M F F A, Harun W S W, Samykano M, Ghani S A C, Ghazalli Z, Ahmad F, Sulong A B
Institute of Postgraduate Studies, Universiti Malaysia Pahang, Lebuhraya Tun Razak, 26300 Gambang, Kuantan, Pahang, Malaysia.
Green Research for Advanced Materials Laboratory, Human Engineering Group, Faculty of Mechanical Engineering, Universiti Malaysia Pahang, 26600 Pekan, Pahang, Malaysia.
Mater Sci Eng C Mater Biol Appl. 2017 Sep 1;78:1263-1276. doi: 10.1016/j.msec.2017.05.016. Epub 2017 May 5.
Biocompatible metals have been revolutionizing the biomedical field, predominantly in human implant applications, where these metals widely used as a substitute to or as function restoration of degenerated tissues or organs. Powder metallurgy techniques, in specific the metal injection moulding (MIM) process, have been employed for the fabrication of controlled porous structures used for dental and orthopaedic surgical implants. The porous metal implant allows bony tissue ingrowth on the implant surface, thereby enhancing fixation and recovery. This paper elaborates a systematic classification of various biocompatible metals from the aspect of MIM process as used in medical industries. In this study, three biocompatible metals are reviewed-stainless steels, cobalt alloys, and titanium alloys. The applications of MIM technology in biomedicine focusing primarily on the MIM process setting parameters discussed thoroughly. This paper should be of value to investigators who are interested in state of the art of metal powder metallurgy, particularly the MIM technology for biocompatible metal implant design and development.
生物相容性金属一直在革新生物医学领域，主要应用于人体植入物，这些金属在该领域被广泛用作退化组织或器官的替代物或功能恢复材料。粉末冶金技术，特别是金属注射成型（MIM）工艺，已被用于制造用于牙科和矫形外科植入物的可控多孔结构。多孔金属植入物允许骨组织在植入物表面向内生长，从而增强固定和恢复效果。本文从医疗行业使用的MIM工艺角度详细阐述了各种生物相容性金属的系统分类。在本研究中，对三种生物相容性金属——不锈钢、钴合金和钛合金进行了综述。MIM技术在生物医学中的应用主要集中在对MIM工艺设定参数进行深入讨论。本文对于对金属粉末冶金技术现状感兴趣的研究人员，特别是对用于生物相容性金属植入物设计和开发的MIM技术的研究人员应具有参考价值。
