H2受体拮抗剂与人类粒细胞生成
H2 receptor antagonists and human granulopoiesis.
作者信息
Aglietta M, Stacchini A, Sanavio F, Piacibello W
出版信息
Experientia. 1985 Mar 15;41(3):375-6. doi: 10.1007/BF02004513.
PMID:2857656
Abstract
The effect of 2 H2 receptor antagonists (ranitidine and cimetidine) on the in vitro growth of human granulomonopoietic precursors (CFU-GM) was studied. Ranitidine, although having an anti H2 receptor activity much greater than that of cimetidine, displays the same toxicity for CFU-GM.
摘要
研究了2种H2受体拮抗剂（雷尼替丁和西咪替丁）对人粒单系造血祖细胞（CFU-GM）体外生长的影响。雷尼替丁虽然具有比西咪替丁更强的抗H2受体活性，但对CFU-GM显示出相同的毒性。
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