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关节软骨磨损的生物治疗选择(富血小板血浆、干细胞、骨髓抽吸浓缩物)

Biologic Options for Articular Cartilage Wear (Platelet-Rich Plasma, Stem Cells, Bone Marrow Aspirate Concentrate).

作者信息

Kraeutler Matthew J, Chahla Jorge, LaPrade Robert F, Pascual-Garrido Cecilia

机构信息

Department of Orthopedics, University of Colorado School of Medicine, 1635 Aurora Ct, Aurora, CO 80045, USA.

Steadman Philippon Research Institute, 181 West Meadow Drive, Suite 400, Vail, CO 81657, USA.

出版信息

Clin Sports Med. 2017 Jul;36(3):457-468. doi: 10.1016/j.csm.2017.02.004. Epub 2017 Apr 1.

DOI:10.1016/j.csm.2017.02.004
PMID:28577706
Abstract

Biological treatments for articular cartilage repair have gained in popularity in the past decade. Advantages of these therapies include minimal invasiveness, improved healing time, and faster recovery. Biological therapies for cartilage repair include platelet-rich plasma, bone marrow aspirate concentrate, and cell-based therapies. These methods have the added benefit of containing growth factors and/or stem cells that aid in recovery and regeneration. The purpose of this article is to review the current cartilage treatment options and the existing literature on outcomes, complications, and safety profile of these products for use in the knee and hip joints.

摘要

在过去十年中,用于关节软骨修复的生物治疗方法越来越受欢迎。这些疗法的优点包括微创性、缩短愈合时间和更快恢复。用于软骨修复的生物疗法包括富血小板血浆、骨髓抽吸浓缩物和基于细胞的疗法。这些方法还有一个额外的好处,即含有有助于恢复和再生的生长因子和/或干细胞。本文的目的是回顾当前的软骨治疗选择以及关于这些产品用于膝关节和髋关节的疗效、并发症和安全性的现有文献。

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