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骨形态发生蛋白：2017年在骨科创伤中仍有作用吗？

Bone Morphogenetic Protein: Is There Still a Role in Orthopedic Trauma in 2017?

作者信息

Barcak Eric A, Beebe Michael J

机构信息

Department of Orthopedic Surgery, University of Tennessee-Campbell Clinic, 1211 Union Avenue #500, Memphis, TN 38104, USA.

Department of Orthopedic Surgery, University of Tennessee-Campbell Clinic, 1211 Union Avenue #500, Memphis, TN 38104, USA.

出版信息

Orthop Clin North Am. 2017 Jul;48(3):301-309. doi: 10.1016/j.ocl.2017.03.004. Epub 2017 Apr 29.

DOI:10.1016/j.ocl.2017.03.004
PMID:28577779
Abstract

Approximately 10 years ago bone morphogenic protein (BMP) was seen as a miraculous adjuvant to assist with bone growth. However, in the face of an increasing number of complications and a lack of understanding its long-term effects, it is unclear what role BMP has in the current treatment of orthopedic trauma patients. This article reviews the current recommendations, trends, and associated complications of BMP use in fracture care.

摘要

大约10年前，骨形态发生蛋白（BMP）被视为促进骨生长的神奇辅助剂。然而，面对越来越多的并发症以及对其长期影响缺乏了解，BMP在目前骨科创伤患者的治疗中究竟扮演什么角色尚不清楚。本文综述了BMP在骨折治疗中的当前推荐、趋势及相关并发症。

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