Allison D J, Jordan H, Hennessy O
Lancet. 1985 Mar 16;1(8429):595-9. doi: 10.1016/s0140-6736(85)92142-7.
In 75 procedures carried out in 57 patients, hepatic arterial embolisation was shown to be a safe and effective treatment for hepatic arterial bleeding and benign vascular tumours and malformations. The median survival of patients with malignant hepatic tumours in our series compares favourably with that recorded for other methods of treatment in patients with similar tumours. Embolisation ameliorated the symptoms produced by malignant hepatic tumours, particularly those occurring in patients with functioning endocrine tumours. The commonest side-effects of embolisation were pain, pyrexia, leucocytosis, intrahepatic gas formation, and nausea. Serious complications were rare and included hepatic abscess (4 patients), septicaemia (2 patients), renal failure (2 patients), and bowel infarction (1 patient). The 2 patients with septicaemia died within a week of embolisation, and these were the only deaths directly attributable to the procedure.
在对57例患者实施的75例手术中,肝动脉栓塞术被证明是治疗肝动脉出血、良性血管肿瘤和畸形的一种安全有效的方法。我们系列研究中恶性肝肿瘤患者的中位生存期与其他治疗类似肿瘤患者的方法所记录的生存期相比具有优势。栓塞术改善了恶性肝肿瘤产生的症状,尤其是那些发生在内分泌功能活跃的肿瘤患者身上的症状。栓塞术最常见的副作用是疼痛、发热、白细胞增多、肝内气体形成和恶心。严重并发症很少见,包括肝脓肿(4例患者)、败血症(2例患者)、肾衰竭(2例患者)和肠梗死(1例患者)。2例败血症患者在栓塞术后一周内死亡,这是仅有的直接归因于该手术的死亡病例。