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结合术中栓塞与即刻切除安全切除巨大肝血管瘤。

Combining On-Table Embolization with Immediate Resection to Safely Excise Giant Hepatic Hemangiomas.

机构信息

Department of Surgery, Division of Surgical Oncology, University of Illinois at Chicago, College of Medicine, 835 S. Wolcott Ave, MC790, Chicago, IL, 60612, USA.

Creticos Cancer Center at Advocate Illinois Masonic Medical Center, Chicago, IL, USA.

出版信息

J Gastrointest Surg. 2021 Jun;25(6):1651-1653. doi: 10.1007/s11605-021-04957-8. Epub 2021 Feb 25.

Abstract

The management of symptomatic giant hepatic hemangiomas (> 10 cm) varies in the literature. Multiple interventional approaches have been described including surveillance, embolization, enucleation, and resection based on tumor size, location, relationship to vascular and biliary structures, and the quality and quantity of the functional liver remnant. Resection is often performed as a last resort due to the risk of major hemorrhage. Preoperative arterial embolization is an option; however, many patients will experience severe pain, fever, transaminitis, acidosis, recanalization, and collateral inflow that limit its utility. Furthermore, patients require post-procedure inpatient observation, and there is no consensus on the appropriate time interval between procedures. We present and demonstrate a technique in the video that utilizes a hybrid operating room with on-table angiogram capabilities to perform hemangioma inflow embolization and immediate hepatic resection under the same anesthesia in a single procedure. Combining on-table embolization with immediate resection avoids many of the pitfalls of preoperative embolization, while enhancing the safety of the resection by decreasing the size of the tumor, enabling compressibility, and facilitating exposure of the vascular inflow and outflow. It is an efficient use of hospital resources and eliminates an intervening hospital admission. We have found it to be a preferred approach to enhance the safety and feasibility of resection for massive hepatic hemangiomas with minimal intraoperative blood loss and reduced risk.

摘要

症状性巨大肝血管瘤(> 10cm)的治疗在文献中有多种方法。根据肿瘤大小、位置、与血管和胆道结构的关系以及功能性肝残留的质量和数量,可采用多种介入方法,包括监测、栓塞、剜除和切除。由于存在大出血的风险,切除通常是最后的手段。术前动脉栓塞是一种选择;然而,许多患者会经历严重的疼痛、发热、肝功能异常、酸中毒、再通和侧支血流增加,限制了其应用。此外,患者需要术后住院观察,并且对于手术之间的适当时间间隔没有共识。我们在视频中展示并演示了一种技术,该技术利用具有术中血管造影功能的杂交手术室,在同一麻醉下进行血管瘤流入栓塞和即刻肝切除术。将术中栓塞与即刻切除相结合,可以避免术前栓塞的许多陷阱,同时通过减小肿瘤大小、增加可压缩性以及促进血管流入和流出的暴露,增强了切除的安全性。这是一种高效利用医院资源的方法,可避免中间的住院治疗。我们发现,这种方法可以增强巨大肝血管瘤切除的安全性和可行性,术中出血量少,风险降低。

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