Sam Kenny Q, Severs Frederick J, Ebuoma Lilian O, Chandandeep Nagi S, Sedgwick Emily L
Department of Diagnostic and Interventional Radiology, Baylor College of Medicine, Houston, USA.
Department of Pathology and Immunology, Baylor College of Medicine, Houston, USA.
J Radiol Case Rep. 2017 Feb 28;11(2):16-22. doi: 10.3941/jrcr.v11i2.2934. eCollection 2017 Feb.
Granulomatous mastitis is a rare and benign inflammatory condition of the breast most commonly affecting women of child-bearing age as well as patients on oral contraceptives. This condition is important to identify due to its diagnostic mimicry of malicious entities such as breast carcinoma. Clinical and radiological findings are nonspecific and may overlap with breast carcinomas, thus pathologic confirmation is often necessary for definitive diagnosis. Although cases of granulomatous mastitis have been described in cisgender females, there have been no reported cases in the transgender patient, a growing patient population with few imaging guidelines. Transgender patients are at risk of developing this breast entity due to the use of long-term hormone treatments or presence of residual breast tissue. A trial of antibiotics or steroids may be administered. However, surgical treatment is often necessary in recurrent or refractory cases.
肉芽肿性乳腺炎是一种罕见的乳腺良性炎症性疾病,最常影响育龄女性以及口服避孕药的患者。由于其在诊断上易与乳腺癌等恶性疾病相混淆,因此识别这种疾病很重要。临床和影像学表现不具有特异性,可能与乳腺癌重叠,因此明确诊断通常需要病理证实。虽然已在顺性别女性中描述了肉芽肿性乳腺炎病例,但在跨性别患者中尚无报告病例,而跨性别患者群体不断增加,却几乎没有影像学指南。由于长期使用激素治疗或存在残留乳腺组织,跨性别患者有发生这种乳腺疾病的风险。可进行抗生素或类固醇试验性治疗。然而,对于复发性或难治性病例,手术治疗往往是必要的。