Sun Changbo, Sun Yanbin, Shen Hui, Yang Chunlu, Xu Shun
Department of Thoracic Surgery, First Hospital of China Medical University, Shenyang, China.
Intractable Rare Dis Res. 2017 May;6(2):80-86. doi: 10.5582/irdr.2017.01014.
Idiopathic pulmonary fibrosis (IPF) is a rare lung disease with a prognosis that can be worse than that of many cancers. Recent studies have improved our understanding of IPF and new treatment options have become available. However, most studies are conducted predominantly in Western countries while few are conducted in East Asian countries. The distribution, effectiveness of treatment, and prognosis for IPF differ among Westerners and East Asians, but whether the heterogeneity of IPF in East Asians is the result of ethnic differences and geographic variability is unclear. This study highlights the current prevalence of IPF and its characteristics in the East Asian population and it provides valuable information to understand the current clinical status of patients with IPF in light of recent advances in its diagnosis and treatment.
特发性肺纤维化（IPF）是一种罕见的肺部疾病，其预后可能比许多癌症还要差。最近的研究增进了我们对IPF的了解，并且有了新的治疗选择。然而，大多数研究主要在西方国家进行，而在东亚国家进行的研究很少。IPF在西方人和东亚人中的分布、治疗效果和预后有所不同，但东亚人IPF的异质性是否是种族差异和地域差异的结果尚不清楚。本研究强调了东亚人群中IPF的当前患病率及其特征，并根据其诊断和治疗的最新进展，为了解IPF患者的当前临床状况提供了有价值的信息。
