James A L, Phillips M J, Thompson P J
Med J Aust. 1985 Mar 4;142(5):293-4.
To assess the adequacy of therapy in asthma, 46 children with asthma attending a summer camp were asked to complete a questionnaire about their symptoms and the treatment that they had received. Each child's height, weight, forced expiratory volume in one second (FEV1) and forced vital capacity (FVC) were measured. According to defined criteria of symptom severity the children were categorized as suffering from severe (48%) or mild (52%) asthma. The mean FEV1/FVC ratio (P less than 0.05) and the mean FEV1 were lower (P less than 0.02) in the children with severe asthma compared with those with mild asthma. In the group with severe asthma, 68% of the children were considered to be receiving suboptimal therapy; 45% had never had their FEV1 or FVC measured. Among those who were receiving suboptimal therapy, 40% had measurable airflow obstruction compared with 17% of children with mild asthma. Because poor management of asthma remains common in children, the need to make doctors and parents aware of the fact that suboptimal therapy may contribute significantly to the morbidity of the condition is emphasized.
为评估哮喘治疗的充分性,我们让46名参加夏令营的哮喘患儿填写了一份关于其症状及所接受治疗的问卷。测量了每个孩子的身高、体重、一秒用力呼气容积(FEV1)和用力肺活量(FVC)。根据症状严重程度的既定标准,将这些儿童分为重度哮喘(48%)或轻度哮喘(52%)患者。与轻度哮喘患儿相比,重度哮喘患儿的平均FEV1/FVC比值更低(P<0.05),平均FEV1也更低(P<0.02)。在重度哮喘组中,68%的患儿被认为接受的治疗不够理想;45%的患儿从未测量过FEV1或FVC。在接受治疗不够理想的患儿中,40%存在可测量的气流受限,而轻度哮喘患儿中这一比例为17%。由于儿童哮喘管理不善的情况仍然普遍存在,因此强调需要让医生和家长认识到治疗不够理想可能会显著增加该病的发病率。