Neonatology and Neonatal Intensive Care Unit, Children Hospital, ASST Spedali Civili, Brescia, Italy.
Acta Paediatr. 2017 Oct;106(10):1564-1568. doi: 10.1111/apa.13944. Epub 2017 Jul 5.
Alleviating pain in neonates should be the goal of all caregivers. We evaluated whether recorded maternal voices were safe and effective in limiting pain in preterm infants undergoing heel lance procedures in the neonatal intensive care unit of an Italian children's hospital.
This prospective, controlled study took place from December 2013 to December 2015. We enrolled 40 preterm infants, born at a 26-34 weeks of gestation, at a corrected gestational age 29-36 weeks and randomised them to listen or not listen to a recording of their mother's voice during a painful, routine heel lance for blood collection. Changes in the infants' Premature Infant Pain Profile, heart rate, oxygen saturation and blood pressure during the procedure were compared by analysis of variance. Possible side effects, of apnoea, bradycardia, seizures and vomiting, were also recorded.
Both groups showed a marked increase in PIPP scores and decrease in oxygen saturation during the procedure, but infants in the treatment group had significantly lower PIPP scores (p = 0.00002) and lower decreases in oxygen saturation (p = 0.0283). No significant side effects were observed.
Using recorded maternal voices to limit pain in preterm infants undergoing heel lance procedures appeared safe and effective.
缓解新生儿的疼痛应成为所有护理人员的目标。我们评估了在意大利一家儿童医院新生儿重症监护病房接受足跟采血的早产儿进行足跟采血时，记录的母亲声音是否安全有效。
这是一项前瞻性、对照研究，于 2013 年 12 月至 2015 年 12 月进行。我们纳入了 40 名胎龄 26-34 周、校正胎龄 29-36 周的早产儿，将他们随机分为在足跟采血时听或不听母亲声音的记录。通过方差分析比较了婴儿在该过程中疼痛评分、心率、血氧饱和度和血压的变化。还记录了可能的副作用，如呼吸暂停、心动过缓、癫痫发作和呕吐。
两组在操作过程中 PIPP 评分均明显升高，血氧饱和度均降低，但治疗组婴儿 PIPP 评分显著降低（p=0.00002），血氧饱和度降低幅度显著降低（p=0.0283）。未观察到明显的副作用。
使用记录的母亲声音来限制接受足跟采血的早产儿的疼痛似乎是安全有效的。
