Shiff Ilana, Bucsea Oana, Pillai Riddell Rebecca
Department of Psychology, York University, Toronto, ON, Canada.
Department of Psychiatry Research, Hospital for Sick Children, Toronto, ON, Canada.
Front Pediatr. 2021 Oct 25;9:568755. doi: 10.3389/fped.2021.568755. eCollection 2021.
Preterm pain is common in the Neonatal Intensive Care Unit (NICU), with multiple invasive procedures occurring daily. To review the psychosocial and neurobiological vulnerabilities of preterm infants and to provide an updated overview of non-pharmacological strategies for acute procedural pain in hospitalized preterm infants. We utilized a narrative review methodology, which also included a synthesis of key pieces of published systematic reviews that are relevant to the current work. Preterm infants are uniquely susceptible to the impact of painful procedures and prolonged separation from caregivers that are often inherent in a NICU stay. Non-pharmacological interventions can be efficacious for mitigating procedural pain for preterm infants. Interventions should continue to be evaluated with high quality randomized controlled trials, and should endeavor to take into account the neurobiological and psychosocial aspects of preterm vulnerability for pain prevention and management strategies.
早产疼痛在新生儿重症监护病房（NICU）很常见，每天都会进行多次侵入性操作。回顾早产儿的心理社会和神经生物学易损性，并提供住院早产儿急性操作疼痛非药物策略的最新概述。我们采用了叙述性综述方法，其中还包括对与当前工作相关的已发表系统综述关键部分的综合。早产儿特别容易受到疼痛操作以及NICU住院期间常有的与照顾者长期分离的影响。非药物干预对减轻早产儿的操作疼痛可能有效。应继续通过高质量随机对照试验对干预措施进行评估，并应努力在疼痛预防和管理策略中考虑早产儿疼痛易损性的神经生物学和心理社会方面。
