Mo Allison, McQuilten Zoe K, Wood Erica M, Weinkove Robert
Supportive Care Disease Group, Australasian Leukaemia and Lymphoma Group, Melbourne, Victoria, Australia.
Department of Haematology, Monash Health, Melbourne, Victoria, Australia.
Intern Med J. 2017 Jun;47(6):695-698. doi: 10.1111/imj.13434.
Optimal red cell transfusion thresholds in myelodysplastic syndrome are not established. In this survey of 110 Australasian haematologists' practice in myelodysplastic syndrome-related anaemia, 92% of respondents set transfusion thresholds, and would typically transfuse at a haemoglobin <80 g/L aiming for a post-transfusion haemoglobin 90-100 g/L, reflecting a restrictive transfusion strategy. Higher thresholds were typically used for patients with cardiovascular disease or anaemia symptoms. These results will inform the design of clinical trials comparing transfusion thresholds.
骨髓增生异常综合征中最佳红细胞输血阈值尚未确定。在这项对110名澳大利亚血液学家治疗骨髓增生异常综合征相关贫血的实践调查中，92%的受访者设定了输血阈值，通常会在血红蛋白<80 g/L时进行输血，目标是使输血后血红蛋白达到90 - 100 g/L，这反映了一种限制性输血策略。对于患有心血管疾病或有贫血症状的患者，通常会采用更高的阈值。这些结果将为比较输血阈值的临床试验设计提供参考。
