Sidney Kimmel Cancer Center of Thomas Jefferson University Hospital, Philadelphia, PA.
Sidney Kimmel Cancer Center of Thomas Jefferson University Hospital, Philadelphia, PA.
Clin Lymphoma Myeloma Leuk. 2019 Dec;19(12):758-762. doi: 10.1016/j.clml.2019.10.001. Epub 2019 Oct 13.
Anemia is the most common cytopenia seen in the myelodysplastic syndromes (MDS). The majority of patients with MDS will require red blood cell (RBC) transfusions during the course of their disease. However, unlike many other disease groups, there is no consensus on the optimal strategy for RBC transfusion in this patient population. In this article, we review the data supporting the use of restrictive transfusion strategies in multiple patient populations and discuss the current literature regarding transfusion management in patients with MDS.
贫血是骨髓增生异常综合征(MDS)中最常见的细胞减少症。大多数 MDS 患者在疾病过程中需要输注红细胞(RBC)。然而,与许多其他疾病群体不同,对于该患者群体中 RBC 输注的最佳策略尚无共识。在本文中,我们回顾了支持在多种患者群体中采用限制性输血策略的数据,并讨论了关于 MDS 患者输血管理的当前文献。