Dougherty William, Givi Babak, Jameson Mark J
Department of Otolaryngology - Head and Neck Surgery, University of Virginia Health System, Charlottesville, Virginia.
Department of Otolaryngology - Head and Neck Surgery, New York University Langone Medical Center, New York, New York.
Head Neck. 2017 Aug;39(8):1505-1509. doi: 10.1002/hed.24817. Epub 2017 Jun 5.
Lip cancer is one of the most curable primary head and neck malignancies, as the prominent location typically lends to an early diagnosis. The incidence of lip cancer varies by sex, ethnicity, and region, but is estimated to be up to 2.5/100 000 in the United States (squamous cell carcinoma [SCC]).
This article will review the current literature and National Comprehensive Cancer Network practice guidelines in the treatment of lip cancer.
Resection of lip cancer with negative margins remains the mainstay of therapy. Positive nodal disease should be treated with neck dissection and adjuvant radiotherapy.
Lip cancer remains highly curable when diagnosed at an early stage. A multidisciplinary approach is crucial to treating patients with advanced-stage lip cancer.
唇癌是最可治愈的原发性头颈部恶性肿瘤之一,因其突出的位置通常便于早期诊断。唇癌的发病率因性别、种族和地区而异,但在美国估计高达每10万人中有2.5例(鳞状细胞癌[SCC])。
本文将综述唇癌治疗方面的当前文献和美国国立综合癌症网络的实践指南。
切缘阴性的唇癌切除仍是主要治疗方法。阳性淋巴结疾病应采用颈部清扫术和辅助放疗。
唇癌早期诊断时仍具有很高的治愈率。多学科方法对于治疗晚期唇癌患者至关重要。