Department of Neurology, Zhejiang Provincial People's Hospital, Hangzhou, China.
Mult Scler. 2017 Dec;23(14):1950-1954. doi: 10.1177/1352458517705479. Epub 2017 Jun 5.
Understanding the characteristics of neuromyelitis optica spectrum disorder (NMOSD) with recurrent short partial transverse myelitis (SPTM), which is very rare, contributes to the differential diagnosis of multiple sclerosis (MS). We present two Chinese aquaporin-4 immunoglobulin G (AQP4-IgG)-seropositive NMOSD cases who had at least twice SPTM during 4 and 6 years of follow-up, respectively. Their SPTMs have been mild and responded well to corticosteroids just like in the case of MS. The findings highlight the need of searching for serum AQP4-IgG (cell-based assay strongly recommended) in patients with recurrent SPTM and suggest that those patients may have a mild acute attack phase and favorable long-term prognosis.
了解复发性短节段横贯性脊髓炎（SPTM）的视神经脊髓炎谱系疾病（NMOSD）的特征，这非常少见，有助于多发性硬化症（MS）的鉴别诊断。我们介绍了两例中国水通道蛋白 4 免疫球蛋白 G（AQP4-IgG）阳性 NMOSD 病例，她们分别在 4 年和 6 年的随访期间至少发生了 2 次 SPTM。她们的 SPTM 症状较轻，糖皮质激素治疗反应良好，类似于 MS 病例。这些发现强调了在复发性 SPTM 患者中寻找血清 AQP4-IgG（强烈推荐细胞基础检测）的必要性，并提示这些患者可能处于轻度急性发作期，具有良好的长期预后。
