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改善使用抗精神病药物儿童的心脏代谢监测。

Improving Cardiometabolic Monitoring of Children on Antipsychotics.

作者信息

Cotes Robert O, Fernandes Nisha K, McLaren Jennifer L, McHugo Gregory J, Bartels Stephen J, Brunette Mary F

机构信息

1 Department of Psychiatry and Behavioral Sciences, Emory University School of Medicine , Atlanta, Georgia .

2 Meridian Psychiatric Partners, LLC, Chicago, Illinois.

出版信息

J Child Adolesc Psychopharmacol. 2017 Dec;27(10):916-919. doi: 10.1089/cap.2017.0034. Epub 2017 Jun 5.

Abstract

OBJECTIVES

This study evaluated changes in cardiometabolic monitoring for children and adolescents who were prescribed an antipsychotic medication in a state mental health system before and after a quality improvement intervention.

METHODS

The intervention included education for prescribers, auditing on metabolic monitoring, and feedback to mental health center leaders regarding their monitoring. Research staff extracted yearly data on cardiometabolic monitoring from randomly selected community mental health center records before and after the intervention. Pre- and postintervention changes in monitoring were assessed with chi-squared tests.

RESULTS

Evidence of past year monitoring increased: for glucose 18.9%-42.1% (χ = 6.75, p < 0.001), for triglycerides 13.5%-31.0% (χ = 4.54, p = 0.033), for cholesterol 13.5%-33.1% (χ = 5.48, p = 0.019), and for weight 67.6%-84.1% (χ = 5.21, p = 0.022). Rates of monitoring for blood pressure and waist circumference increased but not significantly. In both years studied, weight was obtained most frequently and waist circumference was obtained least frequently.

CONCLUSIONS

Monitoring rates significantly improved for four out of six parameters evaluated, but overall monitoring rates remained low at the end of the study period. Prescriber education with audit and feedback may improve cardiometabolic monitoring rates, but research is needed to evaluate barriers to monitoring in children.

摘要

目的

本研究评估了在一项质量改进干预前后,州立精神卫生系统中接受抗精神病药物治疗的儿童和青少年的心脏代谢监测变化。

方法

干预措施包括对开处方者进行教育、对代谢监测进行审核,并向心理健康中心负责人反馈其监测情况。研究人员从干预前后随机选择的社区心理健康中心记录中提取年度心脏代谢监测数据。通过卡方检验评估干预前后监测的变化。

结果

过去一年的监测证据有所增加:血糖监测从18.9%增至42.1%(χ = 6.75,p < 0.001),甘油三酯监测从13.5%增至31.0%(χ = 4.54,p = 0.033),胆固醇监测从13.5%增至33.1%(χ = 5.48,p = 0.019),体重监测从67.6%增至84.1%(χ = 5.21,p = 0.022)。血压和腰围的监测率有所上升,但不显著。在研究的两年中,体重监测频率最高且腰围监测频率最低。

结论

在所评估的六个参数中,有四个参数的监测率显著提高,但在研究期末总体监测率仍然较低。对开处方者进行教育并给予审核和反馈可能会提高心脏代谢监测率,但需要开展研究以评估儿童监测的障碍。

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