Patel Vrushali D, Jadhav Kiran B, Shah Vandana S, Gupta Nidhi D
Department of Oral Pathology and Microbiology, KM Shah Dental College and Hospital, Sumandeep Vidyapeeth, Vadodara, Gujarat, India.
Dent Res J (Isfahan). 2017 Mar-Apr;14(2):125-130.
The aim of the study was to assess the correlation between salivary cotinine level and psychological dependence measured through Fagerstrom test for nicotine dependence (FTND) questionnaire among tobacco users.
This was a cross-sectional study, conducted on tobacco users. Participants with the present habit of tobacco chewing and smoking above the age of 16 years were included in the study. A standard questionnaire form of FTND revised version for smoking and smokeless form of tobacco were given to each participant. Each participant was asked to answer the questions as per their experience of tobacco consumption and calculate the total point score or FTND score. Salivary cotinine level assessment was done using commercial available NicAlert kit.
When salivary cotinine level was correlated with different variables of both groups, it was observed that weak correlation between salivary cotinine level and FTND scoring in smokers group ( = 0.083) and also in smokeless group ( = 0.081). When two groups were compared for salivary cotinine level, statistically significant difference ( = 0.021) was observed, with smokeless group showing high level of salivary cotinine level as compared to smokers group.
Salivary cotinine and psychological dependence through FTND scoring are not strongly correlating with each other. This indicates that dependence over tobacco is a separate phenomenon and cannot be assessed by salivary cotinine level. It is well accepted that salivary cotinine level is influenced by age of individual, duration of habit, and type of tobacco consumption.
本研究的目的是评估烟草使用者唾液中可替宁水平与通过尼古丁依赖Fagerström测试(FTND)问卷测量的心理依赖之间的相关性。
这是一项针对烟草使用者的横断面研究。研究纳入了16岁以上有咀嚼烟草和吸烟习惯的参与者。向每位参与者发放了FTND修订版的吸烟和无烟烟草标准问卷。要求每位参与者根据其烟草消费经历回答问题,并计算总得分或FTND得分。使用市售的NicAlert试剂盒进行唾液可替宁水平评估。
当唾液可替宁水平与两组的不同变量相关时,观察到吸烟者组(=0.083)和无烟组(=0.081)中唾液可替宁水平与FTND评分之间的弱相关性。当比较两组的唾液可替宁水平时,观察到统计学上的显著差异(=0.021),无烟组的唾液可替宁水平高于吸烟者组。
唾液可替宁与通过FTND评分得出的心理依赖之间没有很强的相关性。这表明对烟草的依赖是一种独立的现象,不能通过唾液可替宁水平来评估。唾液可替宁水平受个体年龄、习惯持续时间和烟草消费类型的影响,这一点已得到广泛认可。