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皮肤脑膜瘤:细胞形态学诊断

Cutaneous Meningioma: A Cytomorphological Diagnosis.

作者信息

Kishore Manjari, Kaushal Manju, Bhardwaj Minakshi, Sharma Neha

机构信息

Department of Pathology, PGIMER, Dr. RML Hospital, New Delhi, India.

出版信息

Indian Dermatol Online J. 2017 May-Jun;8(3):201-204. doi: 10.4103/idoj.IDOJ_169_16.

Abstract

Cutaneous meningiomas are rare tumors. These are ectopic meningothelial cells located in the dermis and subcutis, and are usually seen on the scalp. Here, we report the case of a 40-year-old woman who presented with a slowly growing asymptomatic mass over the scalp in the right parieto-occipital region. The lesion was firm, adherent to underlying structures, and covered by normal appearing skin. The cytomorphological features along with histological and immunohistochemical studies showing positivity for epithelial membrane antigen, Vimentin, and S100 helped in making a definitive diagnosis of cutaneous meningioma. No evidence of intracranial meningioma was noted in contrast-enhanced computed tomography of the brain.

摘要

皮肤脑膜瘤是罕见肿瘤。这些是位于真皮和皮下组织的异位脑膜内皮细胞,通常见于头皮。在此,我们报告一例40岁女性病例,该患者右侧顶枕部头皮出现一个生长缓慢的无症状肿块。病变质地硬,与下方结构粘连,表面覆盖外观正常的皮肤。细胞形态学特征以及组织学和免疫组化研究显示上皮膜抗原、波形蛋白和S100呈阳性,有助于明确诊断为皮肤脑膜瘤。脑部增强计算机断层扫描未发现颅内脑膜瘤的证据。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/21eb/5447342/37f6c4e03551/IDOJ-8-201-g001.jpg

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