Bour Agathe, Mouchet Florence, Cadarsi Stéphanie, Silvestre Jérôme, Baqué David, Gauthier Laury, Pinelli Eric
EcoLab, Université de Toulouse, CNRS, INPT, UPS, Toulouse, France.
International Consortium for the Environmental Implications of Nanotechnology (iCEINT), Aix-en-Provence, France.
Environ Sci Pollut Res Int. 2017 Jul;24(20):17081-17089. doi: 10.1007/s11356-017-9346-1. Epub 2017 Jun 5.
We studied the fate and toxicity of two types of CeO NPs (bare or citrate-coated) in environmentally relevant conditions, using large indoor microcosms. Long-term exposure was carried out on a three-leveled freshwater trophic chain, comprising microbial communities as primary producers, chironomid larvae as primary consumers, and amphibian larvae as secondary consumers. Whereas coated NPs preferentially sedimented, bare NPs were mainly found in the water column. However, mass balance indicated low recovery (51.5%) for bare NPs, indicating possible NP loss, against 98.8% of recovery for coated NPs. NPs were rather chemically stable, with less than 4% of dissolution. Chironomid larvae ingested large amounts of NPs and were vectors of contamination for amphibian larvae. Although bioaccumulation in amphibian larvae was important (9.47 and 9.74 mg/kg for bare and coated NPs, respectively), no biomagnification occurred through the trophic chain. Finally, significant genotoxicity was observed in amphibian larvae, bare CeO NPs being more toxic than citrate-coated NPs. ᅟ.
我们利用大型室内微观生态系统，在与环境相关的条件下研究了两种类型的CeO纳米颗粒（裸纳米颗粒或柠檬酸盐包覆纳米颗粒）的归宿和毒性。在一个三级淡水营养链上进行了长期暴露实验，该营养链包括作为初级生产者的微生物群落、作为初级消费者的摇蚊幼虫以及作为次级消费者的两栖类幼虫。柠檬酸盐包覆的纳米颗粒优先沉降，而裸纳米颗粒主要存在于水柱中。然而，质量平衡表明裸纳米颗粒的回收率较低（51.5%），这表明可能存在纳米颗粒损失，而柠檬酸盐包覆纳米颗粒的回收率为98.8%。纳米颗粒化学性质相当稳定，溶解率低于4%。摇蚊幼虫摄取了大量纳米颗粒，是两栖类幼虫的污染载体。尽管两栖类幼虫体内的生物累积很显著（裸纳米颗粒和柠檬酸盐包覆纳米颗粒分别为9.47和9.74毫克/千克），但营养链中未发生生物放大作用。最后，在两栖类幼虫中观察到了显著的遗传毒性，裸CeO纳米颗粒比柠檬酸盐包覆纳米颗粒毒性更大。
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