Peca Stefano, Sinha Richie Siddhartha, Brown Derek Wilson, Smith Wendy Lani
Department of Physics and Astronomy, University of Calgary, Calgary, AB, Canada.
Department of Medical Physics, Tom Baker Cancer Centre, Calgary, AB, Canada.
Technol Cancer Res Treat. 2017 Dec;16(6):956-963. doi: 10.1177/1533034617711519. Epub 2017 Jun 6.
We recently developed a novel, open-source dosimetry that uses the electronic portal imaging device to detect dose delivery discrepancies. We applied our method on patients with rectal cancer treated on a belly board device.
dosimetry was performed on 10 patients with rectal cancer treated prone on the belly board with a 4-field box arrangement. Portal images were acquired approximately once per week from each treatment beam. Our dosimetry method used these images along with the planning CT to reconstruct patient planar dose at isocenter depth.
Our algorithm proved sensitive to dose discrepancies and detected discordances in 7 patients. The majority of these were due to soft tissue differences between planning and treatment, present despite matching to bony anatomy. As a result of this work, quality assurance procedures have been implemented for our immobilization devices.
dosimetry is a powerful quality assurance tool that can detect delivery discrepancies, including changes in patient setup and position. The added information on actual dose delivery may be used to evaluate equipment and process quality and to guide for adaptive radiotherapy.
我们最近开发了一种新型的开源剂量测定法,该方法使用电子射野影像装置来检测剂量输送差异。我们将我们的方法应用于在腹托装置上接受治疗的直肠癌患者。
对10例采用4野盒式照射技术俯卧于腹托上治疗的直肠癌患者进行剂量测定。从每个治疗射束大约每周采集一次射野图像。我们的剂量测定方法利用这些图像以及计划CT来重建等中心深度处的患者平面剂量。
我们的算法被证明对剂量差异敏感,并在7例患者中检测到不一致情况。其中大多数是由于计划和治疗之间的软组织差异,尽管已与骨骼解剖结构匹配,但这种差异仍然存在。这项工作的结果是,我们已经为固定装置实施了质量保证程序。
剂量测定是一种强大的质量保证工具,可检测输送差异,包括患者摆位和体位的变化。关于实际剂量输送的附加信息可用于评估设备和流程质量,并指导自适应放疗。