Ellen and Martin Prosserman Centre for Neuromuscular Diseases, Division of Neurology, Department of Medicine, University Health Network, University of Toronto, General Hospital, Room 5 EB 309, 200 Elizabeth Street, Toronto, Ontario, M5G 2C4, Canada.
Muscle Nerve. 2018 Feb;57(2):240-244. doi: 10.1002/mus.25720. Epub 2017 Jun 27.
Assessing myasthenia gravis (MG) can be challenging, and multiple scales are available to evaluate disease severity. We evaluated the utility of a single, simple question, as part of the MG evaluation: "What percentage of normal do you feel regarding your MG, 0%-100% normal?"
A retrospective chart review of patients attending the neuromuscular clinic from January 2014 to December 2015 was performed. Responses were correlated with symptoms and signs, the Quantitative Myasthenia Gravis Score (QMGS), the Myasthenia Gravis Impairment Index (MGII), and the 15-item Myasthenia Gravis Quality of Life scale (MG-QOL15).
The total cohort included 169 patients. The percentage of normal correlated strongly with limb muscle weakness and MG scales, moderately with bulbar and respiratory symptoms, and weakly with ocular manifestations.
The question, "What percentage of normal do you feel regarding your MG?" is feasible and valid, and can be incorporated easily into routine clinical evaluation. Muscle Nerve 57: 240-244, 2018.
评估重症肌无力 (MG) 具有一定挑战性，目前有多种量表可用于评估疾病严重程度。我们评估了一个简单问题在 MG 评估中的效用：“你感觉自己的 MG 正常程度为多少，正常的 0%-100%？”
对 2014 年 1 月至 2015 年 12 月在神经肌肉科就诊的患者进行回顾性图表审查。将答复与症状和体征、定量重症肌无力评分 (QMGS)、重症肌无力损伤指数 (MGII) 和 15 项重症肌无力生活质量量表 (MG-QOL15) 进行相关性分析。
总队列包括 169 名患者。正常百分比与肢体肌无力和 MG 量表高度相关，与延髓和呼吸症状中度相关，与眼肌表现弱相关。
“你感觉自己的 MG 正常程度为多少，正常的 0%-100%？”这个问题是可行且有效的，可轻松纳入常规临床评估中。《肌肉神经》57: 240-244, 2018。
