National Research Center for Carbohydrate Synthesis, Jiangxi Normal University , Nanchang, Jiangxi 330022, P. R. China.
College of Chemistry and Molecular Sciences, the Institute for Advanced Studies (IAS), Wuhan University , Wuhan, Hubei 430072, P. R. China.
Org Lett. 2017 Jun 16;19(12):3147-3150. doi: 10.1021/acs.orglett.7b01272. Epub 2017 Jun 7.
A novel oxygen-centered radical addition between acyl peroxides and isocyanides has been developed. A diverse collection of valuable arylcarboxyamides were easily synthesized by this protocol. From the preliminary mechanistic study, the elimination of carbon dioxide affords the product via an intramolecular rearrangement.
一种新型的酰基过氧化物和异氰之间的以氧为中心的自由基加成反应已经被开发出来。通过该方法可以很容易地合成出各种各样有价值的芳基羧酰胺。从初步的机理研究来看，通过分子内重排消除二氧化碳得到产物。
