a Department of Thoracic Surgery , University of L'Aquila, "G. Mazzini" Hospital , Teramo , Italy.
Ann Med. 2017 Nov;49(7):626-635. doi: 10.1080/07853890.2017.1339906. Epub 2017 Jun 23.
Solitary pulmonary nodules are common radiologic findings and their detection has increased due to the introduction and improvement of diagnostics. Since a nodule can be an expression of early lung cancers, a proper classification and management are required because its treatment might lead to decreased morbidity and mortality. In this regard, prominent guidelines are available although they are characterized sometimes by discordant and misleading evidences. Furthermore, the same results of studies in the literature appear conflicting. Aim of this work is to evaluate the role of imaging through an extensive literature review but focusing on 18-fluorine fluorodeoxyglucose positron emission tomography combined with computed tomography (F-FDG-PET/CT) in order to assess the limits and future perspectives of solitary pulmonary nodule characterization in early detection of lung cancer. Key messages Detection of solitary pulmonary nodules has increased. Management of solitary pulmonary nodules is still debated. Future perspectives of early solitary pulmonary nodule characterization.
孤立性肺结节是常见的影像学表现，由于诊断技术的引入和改进，其检出率有所增加。由于结节可能是早期肺癌的表现，因此需要进行适当的分类和管理，因为其治疗可能会降低发病率和死亡率。在这方面，虽然存在有时不一致和误导性的证据，但也有一些突出的指南。此外，文献中的相同研究结果似乎也存在矛盾。这项工作的目的是通过广泛的文献回顾来评估影像学的作用，但重点是 18-氟代脱氧葡萄糖正电子发射断层扫描与计算机断层扫描（F-FDG-PET/CT）结合，以评估在早期检测肺癌中孤立性肺结节特征化的局限性和未来前景。
关键信息
孤立性肺结节的检出率有所增加。
孤立性肺结节的管理仍存在争议。
早期孤立性肺结节特征化的未来展望。
