标准化摄取值衍生比值在N2期氟-18氟脱氧葡萄糖正电子发射断层扫描非小细胞肺癌中的当前作用
Current role of standardized uptake value-derived ratios in N2 fluorine-18 fluorodeoxyglucose positron-emission tomography non-small cell lung cancer.
作者信息
Divisi Duilio, Barone Mirko, Crisci Roberto
机构信息
Department of Thoracic Surgery, University of L'Aquila, "G. Mazzini" Hospital, Teramo, Italy.
出版信息
J Thorac Dis. 2018 Jan;10(1):503-507. doi: 10.21037/jtd.2017.11.137.
Abstract
Mediastinal staging is a crucial moment in management of non-small cell lung cancer (NSCLC) patients. In integrated pathways, 18-fluorine fluorodeoxyglucose positron-emission tomography (F-FDG-PET/CT) is an indispensable imaging resource with its peculiarities and its limitations. A critical review of work up protocols would certainly help to standardize procedures with important reflections also on the diagnostic value of this examination. In this regard, new semi-quantitative and semi-qualitative indexes have been proposed with the aim of increasing the accuracy of F-FDG-PET/CT in mediastinal lymph node staging. These latter, such as SUV and SUV indexes, seem to overcome the problem of spatial resolution and discrimination of malignancy by endorsing a new predictive and prognostic role.
摘要
纵隔分期是非小细胞肺癌（NSCLC）患者治疗过程中的关键环节。在综合诊疗路径中，18氟氟脱氧葡萄糖正电子发射断层扫描（F-FDG-PET/CT）作为一种不可或缺的影像检查手段，有其独特之处和局限性。对检查方案进行批判性审视无疑有助于规范操作流程，同时也能对该项检查的诊断价值进行重要反思。在这方面，已经提出了新的半定量和半定性指标，旨在提高F-FDG-PET/CT在纵隔淋巴结分期中的准确性。后者，如SUV及SUV相关指标，似乎通过赋予新的预测和预后作用，克服了空间分辨率及恶性肿瘤鉴别方面的问题。
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