Keyser-Marcus Lori, Vassileva Jasmin, Stewart Karen, Johns Sade
a Institute for Drug and Alcohol Studies, Department of Psychiatry , Virginia Commonwealth University , Richmond , VA , USA.
b Department of Psychiatry and Behavior Sciences , Vanderbilt University Medical Center , Nashville , TN , USA.
Am J Drug Alcohol Abuse. 2017 Jul;43(4):432-441. doi: 10.1080/00952990.2017.1287190. Epub 2017 Mar 1.
Smoking remains one of the most preventable causes of morbidity and mortality in the United States (1). A number of factors contribute to the initiation and maintenance of smoking behavior, including psychosocial influences (2,3), neurobehavioral traits (4), and genetic susceptibility (5-7). Prevalence rates of tobacco dependence among individuals with mental health issues are strikingly high when compared to the general population, particularly among individuals with depression and anxiety disorders (8). There are well-established relationships between impulsivity, cue reactivity, and tobacco use in the literature (9). However, the interaction between these relationships remains unclear. The primary goal of this paper is to provide an overview of the existing literature across these domains and explore their interrelationship and subsequent impact on smoking initiation and tobacco dependence. Further, the clinical implications regarding the development of potential targeted smoking cessation strategies for this population are presented.
在美国，吸烟仍然是发病率和死亡率的最可预防原因之一(1)。多种因素导致吸烟行为的开始和持续，包括社会心理影响(2,3)、神经行为特征(4)和遗传易感性(5 - 7)。与普通人群相比，有心理健康问题的个体中烟草依赖的患病率极高，尤其是在患有抑郁症和焦虑症的个体中(8)。文献中已明确冲动性、线索反应性与烟草使用之间的关系(9)。然而，这些关系之间的相互作用仍不清楚。本文的主要目标是概述这些领域的现有文献，并探讨它们的相互关系以及对吸烟开始和烟草依赖的后续影响。此外，还介绍了针对该人群制定潜在的靶向戒烟策略的临床意义。
