Alqahtani Mohammed M, Alanazi Abdullah M M, Aljohani Hassan, Ismaeil Taha T, Algarni Saleh S, Alotaibi Tareq F, Alotaibi Mansour M, Kalan Mohammad Ebrahimi, Lein Donald H, Alqahtani Mobarak K, Alwadeai Khalid S, Almutairi Anwar B, Hendricks Peter S
Department of Respiratory Therapy, College of Applied Medical Sciences, King Saud bin Abdulaziz University for Health Sciences, Riyadh, Saudi Arabia.
King Abdullah International Medical Research Center, Riyadh, Saudi Arabia.
Tob Induc Dis. 2023 Sep 22;21:116. doi: 10.18332/tid/169741. eCollection 2023.
There is a paucity of studies on e-cigarette use among adults with chronic lung disease. In the present study, we aimed to assess whether psychosocial or cognitive factors elucidate the relationship between chronic lung disease (CLD) and susceptibility to e-cigarette use and whether the relationship between CLD and e-cigarette use is conditional on the presence of respiratory symptoms.
We recruited adults aged ≥18 years in Alabama with CLD from university medical clinics (n=140) and individuals without CLD (n=123 as a reference group). Information on sociodemographics, susceptibility to e-cigarette use, psychosocial factors, and cognitive factors were collected. Mediation analysis was used to assess whether the psychosocial factors or cognitive factors explained the association between CLD and susceptibility to using e-cigarettes, and moderation analysis was conducted to determine if respiratory factors would change the association between CLD and susceptibility to e-cigarette use.
Psychosocial factors (stress, depression, anxiety) and e-cigarette positive expectancy were notably high among individuals with CLD. Having CLD was associated with a lower likelihood of susceptibility to e-cigarette use. Higher levels of stress, being a smoker, boredom, taste/sensorimotor manipulation, and social facilitation were associated with higher odds of susceptibility to using e-cigarettes among individuals with CLD. Mediation analysis indicated a statistically significant indirect effect of CLD on the susceptibility to using e-cigarettes through stress and boredom reduction. We did not find a statistically significant interaction between CLD and respiratory symptoms affecting susceptibility to using e-cigarettes.
Individuals with CLD often exhibit stress, depression, and a positive view of e-cigarettes but are generally less inclined to use them. Stress, smoking habits, boredom, taste, and social influence can increase their susceptibility to e-cigarette use. Our findings call for further exploration to evaluate the temporal relationship between CLD status, psychosocial factors, cognitive factors, and susceptibility to using e-cigarettes.
The study was registered on ClinicalTrials.gov, on 5 November 2019. Identifier: NCT04151784.
关于慢性肺病成年人使用电子烟的研究较少。在本研究中，我们旨在评估心理社会因素或认知因素是否能阐明慢性肺病（CLD）与电子烟使用易感性之间的关系，以及CLD与电子烟使用之间的关系是否取决于呼吸道症状的存在。
我们从大学医疗诊所招募了阿拉巴马州年龄≥18岁的患有CLD的成年人（n = 140）以及没有CLD的个体（n = 123作为参照组）。收集了社会人口统计学、电子烟使用易感性、心理社会因素和认知因素等方面的信息。采用中介分析来评估心理社会因素或认知因素是否解释了CLD与使用电子烟易感性之间的关联，并进行调节分析以确定呼吸道因素是否会改变CLD与电子烟使用易感性之间的关联。
CLD患者的心理社会因素（压力、抑郁、焦虑）和对电子烟的积极预期显著较高。患有CLD与较低的电子烟使用易感性相关。较高水平的压力、吸烟者身份、无聊、口味/感觉运动操控以及社会促进与CLD患者使用电子烟的较高易感性几率相关。中介分析表明，CLD通过减轻压力和无聊对使用电子烟的易感性具有统计学上显著的间接影响。我们没有发现CLD与呼吸道症状之间在影响电子烟使用易感性方面存在统计学上显著的相互作用。
CLD患者常表现出压力、抑郁以及对电子烟的积极看法，但总体上不太倾向于使用电子烟。压力、吸烟习惯、无聊、口味和社会影响会增加他们使用电子烟的易感性。我们的研究结果呼吁进一步探索，以评估CLD状态、心理社会因素、认知因素与使用电子烟易感性之间的时间关系。
该研究于2019年11月5日在ClinicalTrials.gov上注册。标识符：NCT04151784。
