Loyola University Medical Center, Maywood.
Edward Hines Jr Veterans Affairs Hospital, Hines, Illinois.
Clin Infect Dis. 2017 Oct 15;65(8):1396-1399. doi: 10.1093/cid/cix529.
We retrospectively studied vancomycin taper and pulse treatment on 100 consecutive, evaluable patients with recurrent Clostridium difficile infection. Following taper to once-daily vancomycin dosing, 22 of 36 patients (61%) who received every-other-day dosing (QOD) and 50 of 64 (81%) who received QOD followed by every-third-day dosing were cured (P = .03).
我们回顾性研究了万古霉素减量和脉冲治疗对 100 例复发性艰难梭菌感染的连续、可评估患者的影响。在减量至每日一次万古霉素给药后，接受隔日（QOD）给药的 36 例患者中有 22 例（61%）和接受 QOD 后每三天一次（Q3D）给药的 64 例患者中有 50 例（81%）治愈（P =.03）。
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