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[老年女性晚期恶性纵隔非精原细胞瘤的成功联合治疗方案]

[Successful Combined Modality Therapy for an Advanced Malignant Mediastinal Non-seminomatous Germ Cell Tumor in an Elderly Female].

作者信息

Suzuki Hirotoshi, Araki Osamu, Minowa Muneo, Matsuura Yoshifumi, Matsumura Yuji

机构信息

Department of Thoracic Surgery, Institute of Development, Aging and Cancer, Tohoku University, Sendai, Japan.

出版信息

Kyobu Geka. 2017 Jun;70(6):430-433.

PMID:28595223
Abstract

A 69-year-old woman was diagnosed with a germ cell tumor in the anterior mediastinum. Following 3 years follow-up, she experienced chest pain and an enlarging of the anterior mediastinal tumor and bilateral lung metastases were detected by chest X-ray. The tumor was diagnosed as a primary malignant mediastinal non-seminomatous germ cell tumor by needle biopsy. After initial radiotherapy (12 Gy/4 Fr), she was subsequently treated with EP chemotherapy which achieved a partial response. Complete resection of the residual tumors in the mediastinum and right lung was performed. No recurrence has been noted for 5 years post-operatively.

摘要

一名69岁女性被诊断为前纵隔生殖细胞肿瘤。经过3年随访,她出现胸痛,前纵隔肿瘤增大,胸部X线检查发现双侧肺转移。经针吸活检,肿瘤被诊断为原发性恶性纵隔非精原细胞瘤性生殖细胞肿瘤。初始放疗(12 Gy/4次分割)后,她随后接受EP化疗,获得部分缓解。对纵隔和右肺的残留肿瘤进行了完整切除。术后5年未见复发。

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