一项评估帕金森病患者体力活动与认知之间关联的初步研究。
A pilot study evaluating the association between physical activity and cognition among individuals with Parkinson's disease.
机构信息
Department of Health, Exercise Science and Recreation Management, The University of Mississippi, USA.
Department of Physical Therapy, Bellarmine University, USA.
出版信息
Disabil Health J. 2018 Jan;11(1):165-168. doi: 10.1016/j.dhjo.2017.05.004. Epub 2017 Jun 1.
BACKGROUND
Few studies have examined the association between daily physical activity and cognitive function among older adults with Parkinson's disease (PD).
OBJECTIVE
Here we evaluate the association between accelerometer-assessed physical activity and cognition among older patients with PD.
METHODS
Cognition assessed via the Montreal Cognitive Assessment (MoCA). Moderate-to-vigorous physical activity (MVPA) was assessed via accelerometry over a 1-2 week monitoring period.
RESULTS
After adjusting for motor impairment severity, for every 1 min/day increase in MVPA, participants had a 0.09 unit increase in MoCA-determined cognitive function (β = 0.09; 95% CI: -0.003-0.19; P = 0.05). When further adjusting for motor impairment, age and gender, results were unchanged (β = 0.09; 95% CI: 0.004-0.19; P = 0.04).
CONCLUSION
The present study provides suggestive evidence of a favorable association between daily physical activity behavior and cognitive function among adults with PD.
背景
很少有研究探讨帕金森病（PD）老年患者的日常体力活动与认知功能之间的关系。
目的
本研究评估了通过加速度计评估的体力活动与老年 PD 患者认知功能之间的关系。
方法
通过蒙特利尔认知评估（MoCA）评估认知功能。在 1-2 周的监测期间，通过加速度计评估中等到剧烈的体力活动（MVPA）。
结果
在调整运动障碍严重程度后，MVPA 每天增加 1 分钟，MoCA 测定的认知功能增加 0.09 个单位（β=0.09；95%CI：-0.003-0.19；P=0.05）。当进一步调整运动障碍、年龄和性别时，结果保持不变（β=0.09；95%CI：0.004-0.19；P=0.04）。
结论
本研究提供了有力的证据，表明 PD 成年人的日常体力活动行为与认知功能之间存在有利关联。
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