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容积弧形调强放疗用于全头皮照射:头皮复发性基底细胞癌病例报告

Volumetric arc therapy for total scalp irradiation: case report for a recurrent basal cell carcinoma of the scalp.

作者信息

Lozano Francisco, Perez Naipy, Iglesias Alejandro, Xu Xiaodong, Amendola Marco A, Scott Michael, Companioni Erich, Amendola Beatriz E

机构信息

Innovative Cancer Institute, 5995 SW 71st Street, South Miami, FL 33143, USA.

出版信息

Ecancermedicalscience. 2017 May 11;11:737. doi: 10.3332/ecancer.2017.737. eCollection 2017.

Abstract

Total scalp irradiation may be used to treat numerous conditions including squamous and basal cell carcinomas. These conditions are relatively uncommon and patients are frequently treated with palliative intent. In this report, we describe a volumetric arc therapy technique using photon beams for curative intent in an 84 years old patient with recurrent basal cell carcinoma of the scalp. Dose was 50Gy (2Gy per session) to the planning target volume (PTV) followed by a 10 Gy boost to the macroscopic disease on the forehead. A custom made 1 cm superflab bolus helmet was used. Toxicities only consisted of Grade-1 transient radiation dermatitis and alopecia. A sustained clinical response was observed at 6 months follow-up. Volumetric arc therapy (VMAT) may offer an effective alternative modality to treat patients with very extensive scalp lesions as described in this case report.

摘要

全头皮照射可用于治疗多种病症,包括鳞状细胞癌和基底细胞癌。这些病症相对不常见,患者通常接受姑息性治疗。在本报告中,我们描述了一种容积弧形调强放疗技术,使用光子束对一名84岁复发性头皮基底细胞癌患者进行根治性治疗。计划靶区(PTV)剂量为50Gy(每次2Gy),随后对前额肉眼可见的病灶追加10Gy剂量。使用了定制的1厘米厚的超软质组织等效物头盔。毒性反应仅包括1级短暂性放射性皮炎和脱发。随访6个月时观察到持续的临床缓解。如本病例报告所述,容积弧形调强放疗(VMAT)可能为治疗头皮广泛病变的患者提供一种有效的替代治疗方式。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c4b2/5440184/fbac5be19b6e/can-11-737fig1.jpg

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