Suzumura Kazuhiro, Hatano Etsuro, Okada Toshihiro, Asano Yasukane, Uyama Naoki, Nakamura Ikuo, Hai Seikan, Fujimoto Jiro
Department of Surgery, Hyogo College of Medicine, 1-1 Mukogawa-cho, Nishinomiya, Hyogo, 663-8501, Japan.
Surg Today. 2018 Jan;48(1):58-65. doi: 10.1007/s00595-017-1548-0. Epub 2017 Jun 8.
To evaluate the short- and long-term outcomes of the Frey procedure for chronic pancreatitis (CP).
The subjects of this study were 12 patients who underwent the Frey procedure for CP between January, 2000 and December, 2016. We assessed pain relief, weight gain, and exocrine/endocrine insufficiency during follow-up.
The study population comprised 11 men and 1 woman (91.7% vs. 8.3%; mean age, 50.3 ± 6.8 years; range 39-61 years). Pancreatitis was caused by alcohol in 9 (75%) patients and was idiopathic in 3 (25%) patients. The mean follow-up period was 82.5 ± 46.5 months (range 16.9-152.1 months). There was no operative mortality, but three patients (25%) suffered postoperative morbidity. All patients were pain-free at the time of discharge. There was no case of new-onset diabetes mellitus after surgery, although one patient (8.3%) suffered exocrine insufficiency. The body weight and body mass index of all patients improved during follow-up. Only one patient continued to suffer pain in the long term.
The findings of this long-term follow-up of patients who underwent the Frey procedure suggest that it offers effective pain relief and is a safe technique for the management of CP.
评估弗雷氏手术治疗慢性胰腺炎（CP）的短期和长期疗效。
本研究的对象为2000年1月至2016年12月期间接受弗雷氏手术治疗CP的12例患者。我们在随访期间评估了疼痛缓解情况、体重增加情况以及外分泌/内分泌功能不全情况。
研究人群包括11名男性和1名女性（91.7%对8.3%；平均年龄50.3±6.8岁；范围39 - 61岁）。9例（75%）患者的胰腺炎由酒精引起，3例（25%）患者为特发性。平均随访期为82.5±46.5个月（范围16.9 - 152.1个月）。无手术死亡，但3例患者（25%）发生术后并发症。所有患者出院时均无疼痛。术后无新发糖尿病病例，尽管1例患者（8.3%）出现外分泌功能不全。所有患者的体重和体重指数在随访期间均有所改善。只有1例患者长期持续疼痛。
对接受弗雷氏手术患者的长期随访结果表明，该手术能有效缓解疼痛，是治疗CP的一种安全技术。
