2016年12月至2017年5月，德国由产志贺毒素的山梨醇发酵型大肠杆菌O157引发的溶血性尿毒综合征（HUS）持续爆发。
Ongoing haemolytic uraemic syndrome (HUS) outbreak caused by sorbitol-fermenting (SF) Shiga toxin-producing Escherichia coli (STEC) O157, Germany, December 2016 to May 2017.
作者信息
Vygen-Bonnet Sabine, Rosner Bettina, Wilking Hendrik, Fruth Angelika, Prager Rita, Kossow Annelene, Lang Christina, Simon Sandra, Seidel Juliane, Faber Mirko, Schielke Anika, Michaelis Kai, Holzer Alexandra, Kamphausen Rolf, Kalhöfer Daniela, Thole Sebastian, Mellmann Alexander, Flieger Antje, Stark Klaus
机构信息
Robert Koch-Institute, Department of Infectious Diseases Epidemiology, Berlin, Germany.
Robert Koch-Institute, Department of Infectious Diseases, National Reference Centre for Salmonella and other Bacterial Enteric Pathogens, Wernigerode, Germany.
出版信息
Euro Surveill. 2017 May 25;22(21). doi: 10.2807/1560-7917.ES.2017.22.21.30541.
We report an ongoing, protracted and geographically dispersed outbreak of haemolytic uraemic syndrome (HUS) and gastroenteritis in Germany, involving 30 cases since December 2016. The outbreak was caused by the sorbitol-fermenting immotile variant of Shiga toxin-producing (STEC) Escherichia coli O157. Molecular typing revealed close relatedness between isolates from 14 cases. One HUS patient died. Results of a case-control study suggest packaged minced meat as the most likely food vehicle. Food safety investigations are ongoing.
我们报告了德国正在发生的、持续时间长且地域分散的溶血性尿毒综合征（HUS）和肠胃炎疫情，自2016年12月以来已涉及30例病例。此次疫情由产志贺毒素大肠杆菌（STEC）O157的山梨醇发酵无动力变种引起。分子分型显示，14例病例的分离株之间密切相关。一名HUS患者死亡。一项病例对照研究结果表明，包装碎肉是最有可能的食物载体。食品安全调查正在进行中。
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