Division of Infectious Diseases, National Institute of Infectious Diseases and Vaccinology, National Health Research Institutes, Tainan, Taiwan.
J Microbiol Immunol Infect. 2011 Oct;44(5):390-3. doi: 10.1016/j.jmii.2011.07.001. Epub 2011 Sep 8.
Since early May 2011, a large outbreak of enterohemorrhagic gastroenteritis and hemolytic uremic syndrome (HUS) related to infections with Shiga toxin-producing Escherichia coli O104:H4 (STEC O104:H4) had been reported in Germany, which marks one of the largest outbreaks ever described of the HUS worldwide. The HUS outbreak was unusual, and there were important differences between this outbreak and previous large outbreaks, primarily those of STEC O157:H7 both clinically and microbiologically. This outbreak highlights the importance of collaboration of all aspects of public health to detect the outbreak, to identify and characterize the causative agent, to find the vehicles of transmission, and to control the infection.
自 2011 年 5 月初以来，德国报告了一起与产志贺毒素大肠埃希菌 O104:H4（STEC O104:H4）感染相关的大规模肠出血性结肠炎和溶血尿毒综合征（HUS）暴发，这是全球范围内有记录的最大规模 HUS 暴发之一。此次 HUS 暴发不同寻常，与以往的大型暴发，特别是产志贺毒素大肠埃希菌 O157:H7 的暴发，在临床和微生物学方面存在重要差异。此次暴发突显了公共卫生各方面合作的重要性，以发现暴发、确定并描述病原体、发现传播媒介以及控制感染。
