Gu Dunyin, Tan Shereen, Xu Chenglong, O'Connor Andrea J, Qiao Greg G
Department of Chemical and Biomolecular Engineering, The University of Melbourne, Parkville, Victoria 3010, Australia.
Chem Commun (Camb). 2017 Jun 20;53(50):6756-6759. doi: 10.1039/c7cc02811c.
By precisely tuning the network architecture, tough, highly compressible hydrogels were engineered. The hydrogels were made by interconnecting high-functionality hydrophobic domains through linear tri-block chains, consisting of soft hydrophilic middle blocks, flanked with flexible hydrophobic blocks. In showing their applicability, the efficient encapsulation and prolonged release of hydrophobic drugs were achieved.
通过精确调整网络结构，制备出了坚韧、高度可压缩的水凝胶。这些水凝胶是通过线性三嵌段链连接高功能性疏水域制成的，该链由柔软的亲水性中间嵌段组成，两侧是柔性疏水嵌段。在展示其适用性时，实现了疏水药物的高效包封和长效释放。
