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软饮料消费与非酒精性脂肪性肝病风险

Soft Drinks Consumption and the Risk of Nonalcoholic Fatty Liver Disease.

作者信息

Siddiqi Zeba, Karoli Ritu, Fatima Jalees, Khanduri Sachin, Varshneya Shishir, Ahmad Sara Sabina

机构信息

Associate Professor.

Professor.

出版信息

J Assoc Physicians India. 2017 May;65(5):28-32.

PMID:28598045
Abstract

INTRODUCTION

The increased consumption of sugar-sweetened beverages (SSBs) has been implicated in the increased incidence of obesity and metabolic syndrome Little of the research on sugar-sweetened beverage intake has examined the consumption patterns of sugared beverages by college students, despite the vulnerabilities of this population to weight gain. The current study sought to characterize sugar-sweetened beverage intake of undergraduate students who belong to high socio-economic strata and to study its correlation with presence of non-alcoholic fatty liver disease.

MATERIAL AND METHODS

In a cross sectional, a self reported questionnaire based study about soft drink consumption (≥2/day, 1/day, <1/day). That included undergraduate medical students. Anthropometry and blood pressure were recorded and fasting glucose, insulin and lipid profile and abdominal ultrasonography for the presence of fatty liver was assessed.

RESULTS

A total of 242 students were studied. The students in group 1 (≥2/day) had significantly higher BMI, waist circumference and diastolic blood pressure than students of other groups. They also had higher triglycerides, fasting insulin, HOMA-IR and significantly lower levels of HDL-cholesterol. Overall (40%) students had metabolic syndromes in group 1 compared to 8% and 3% in other groups while presence of NAFLD was observed in 75%, 16% and 4% in three groups respectively. Duration of soft drink consumption had positive correlation with presence of NAFLD.

CONCLUSIONS

Substantial consumption of soft drinks is leading to increased obesity and cardio-metabolic risk factors in young adults. Artificially sweetened diet soft drinks have been posed as a healthier alternative due to their lack of calories but they do not guarantee protection against non-alcoholic fatty liver disease.

摘要

引言

含糖饮料(SSB)消费的增加与肥胖和代谢综合征发病率的上升有关。尽管大学生群体易出现体重增加的情况,但很少有关于含糖饮料摄入量的研究考察过大学生饮用含糖饮料的消费模式。本研究旨在描述来自高社会经济阶层的本科生的含糖饮料摄入量,并研究其与非酒精性脂肪性肝病的相关性。

材料与方法

在一项横断面研究中,通过一份基于自我报告的问卷来调查软饮料消费情况(≥2天/次、1天/次、<1天/次)。研究对象包括本科医学生。记录人体测量数据和血压,并评估空腹血糖、胰岛素、血脂水平以及通过腹部超声检查是否存在脂肪肝。

结果

共研究了242名学生。第1组(≥2天/次)的学生的体重指数、腰围和舒张压显著高于其他组的学生。他们的甘油三酯、空腹胰岛素、稳态模型评估的胰岛素抵抗指数也更高,而高密度脂蛋白胆固醇水平显著更低。总体而言,第1组中有40%的学生患有代谢综合征,相比之下,其他组分别为8%和3%,而三组中分别有75%、16%和4%的学生存在非酒精性脂肪性肝病。软饮料消费时长与非酒精性脂肪性肝病的存在呈正相关。

结论

大量饮用软饮料会导致年轻人肥胖增加和心血管代谢风险因素上升。人工甜味的低热量软饮料因其不含热量而被视为更健康的选择,但它们并不能保证预防非酒精性脂肪性肝病。

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