已发表的阿普唑仑临床研究简要综述。
Brief review of published alprazolam clinical studies.
作者信息
Straw R N
出版信息
Br J Clin Pharmacol. 1985;19 Suppl 1(Suppl 1):57S-59S. doi: 10.1111/j.1365-2125.1985.tb02743.x.
Abstract
The clinical efficacy of alprazolam has been evaluated in both anxiety states and depressive disorders. In anxiety neurosis, studies have been conducted vs placebo and/or other benzodiazepine tranquilizers. Reports, to date, with regard to panic/phobia disorders have been limited to open-label studies and a single report from a placebo-controlled study. In depression, both open-label and double-blind studies (vs tricyclic antidepressants) have been published.
摘要
阿普唑仑的临床疗效已在焦虑状态和抑郁障碍中进行了评估。在焦虑性神经症中，已开展了与安慰剂和/或其他苯二氮䓬类镇静剂对比的研究。迄今为止，关于惊恐/恐惧症的报告仅限于开放标签研究和一项安慰剂对照研究的单一报告。在抑郁症方面，已发表了开放标签和双盲研究（与三环类抗抑郁药对比）。
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