阿普唑仑用于伴有情绪低落的临床焦虑患者。
Alprazolam in clinically anxious patients with depressed mood.
作者信息
Aden G C
出版信息
J Clin Psychiatry. 1983 Jan;44(1):22-4.
PMID:6130082
Abstract
A double-blind study compared alprazolam and placebo in 462 clinically anxious patients with accompanying depressed mood. Alprazolam was more effective than placebo as measured by the Hamilton Anxiety Rating Scale, the Self-Rating Symptom Scale, Target Symptoms, Physician's Global Impressions, and Patient's Global Impressions. Alprazolam was not significantly different from placebo in the number of patients reporting drowsiness, the most frequent side effect.
摘要
一项双盲研究对462名伴有抑郁情绪的临床焦虑患者使用阿普唑仑和安慰剂进行了比较。通过汉密尔顿焦虑量表、自评症状量表、目标症状、医生整体印象和患者整体印象评估，阿普唑仑比安慰剂更有效。在报告嗜睡（最常见的副作用）的患者数量方面，阿普唑仑与安慰剂没有显著差异。
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