Frank Jacqueline, Baljić Izet, Hoth Sebastian, Eßer Dirk, Guntinas-Lichius Orlando
a Department of Otorhinolaryngology , Jena University Hospital , Jena , Germany.
b Department of Otorhinolaryngology , Helios Klinikum Erfurt , Erfurt , Germany , and.
Int J Audiol. 2017 May;56(5):337-345. doi: 10.1080/14992027.2017.1281442. Epub 2017 Feb 26.
The hearing threshold at 500 Hz was estimated using five methods which are suitable for the low frequency range: Low-Chirp BERA (LCBERA), Notched-noise BERA (NNBERA), Narrow band CE-Chirp BERA (NBCBERA) and Narrow band CE-Chirp ASSR (NBCASSR) (40/90 Hz). The slope of the discrimination function of each method was used for determination of the most efficient method. The threshold values were compared and the corresponding odds ratios (OR) were calculated.
All methods were applied to each subject. Stimulus levels were arranged individually. Response detection was carried out by visual inspection of the records in case of BERA and automatically in case of ASSR. Each individual series of recordings was converted to a dichotomous function indicating whether or not a response was discernible and a continuous method-specific discrimination function was constructed. This function was realised by a Boltzmann function whose slope in the inflection point serves as quality measure. Additionally, an OR evaluation was carried out in order to validate the significance of results.
Twenty five normal hearing adults (aged 18-30 years) were tested.
LCBERA proved to have the highest reliability according to the slope of the Boltzmann function, the comparison of threshold values and OR.
The LCBERA is recommended for use in routine clinical practice.
使用五种适用于低频范围的方法估计500赫兹时的听力阈值:低啁啾脑干听觉诱发电位(LCBERA)、陷波噪声脑干听觉诱发电位(NNBERA)、窄带CE啁啾脑干听觉诱发电位(NBCBERA)和窄带CE啁啾听觉稳态反应(NBCASSR)(40/90赫兹)。每种方法的辨别函数斜率用于确定最有效的方法。比较阈值并计算相应的优势比(OR)。
所有方法均应用于每个受试者。刺激水平单独安排。对于脑干听觉诱发电位,通过目视检查记录来进行反应检测;对于听觉稳态反应,则自动进行检测。将每个单独的记录系列转换为一个二分函数,表明是否可辨别出反应,并构建一个特定方法的连续辨别函数。该函数由玻尔兹曼函数实现,其拐点处的斜率用作质量度量。此外,进行了优势比评估以验证结果的显著性。
对25名听力正常的成年人(年龄18 - 30岁)进行了测试。
根据玻尔兹曼函数的斜率、阈值比较和优势比,LCBERA被证明具有最高的可靠性。
建议在常规临床实践中使用LCBERA。