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鸡胰腺中胰多肽及其他激素的区域分布:胰多肽与胰高血糖素之间的相互关系

Regional distribution of pancreatic polypeptide and other hormones in chicken pancreas: reciprocal relationship between pancreatic polypeptide and glucagon.

作者信息

Tomita T, Doull V, Pollock H G, Kimmell J R

出版信息

Gen Comp Endocrinol. 1985 May;58(2):303-10. doi: 10.1016/0016-6480(85)90346-6.

DOI:10.1016/0016-6480(85)90346-6
PMID:2860049
Abstract

Tissue extracts of discrete lobes of chicken pancreas were assayed for pancreatic polypeptide (PP), glucagon, somatostatin (SRIF), and insulin by radioimmunoassay. Concentrations of all pancreatic hormones except PP were highest in the splenic lobe. PP concentration was greatest in the inferior portions of the three major lobes. There is a reciprocal relationship between PP and glucagon concentration in chicken pancreas. The results with extracts were substantiated by cell frequency measurements using immunocytochemical methods.

摘要

采用放射免疫分析法对鸡胰腺离散叶的组织提取物进行了胰多肽(PP)、胰高血糖素、生长抑素(SRIF)和胰岛素的检测。除PP外,所有胰腺激素的浓度在脾叶中最高。PP浓度在三个主要叶的下部最大。鸡胰腺中PP和胰高血糖素浓度之间存在相互关系。提取物的结果通过免疫细胞化学方法进行细胞频率测量得到了证实。

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Gen Comp Endocrinol. 1985 May;58(2):303-10. doi: 10.1016/0016-6480(85)90346-6.
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