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非冬眠和冬眠金黄地鼠体内的胰腺激素

Pancreatic hormones in the nonhibernating and hibernating golden mantled ground squirrel.

作者信息

Bauman W A, Meryn S, Florant G L

出版信息

Comp Biochem Physiol A Comp Physiol. 1987;86(2):241-4. doi: 10.1016/0300-9629(87)90324-0.

DOI:10.1016/0300-9629(87)90324-0
PMID:2881667
Abstract

The effects of hibernation on pancreatic insulin, glucagon, somatostatin, and pancreatic polypeptide was investigated in the golden mantled ground squirrel (Citellus lateralis). During hibernation, pancreatic organ weight decreased to 57% of the nonhibernating weight. The content of all four pancreatic hormones during hibernation was significantly reduced. The concentrations of insulin, pancreatic polypeptide and somatostatin, but not of glucagon, were significantly reduced during hibernation. The maintenance of the pancreatic glucagon concentration during hibernation may be related to its role in counter-regulation and carbohydrate homeostasis during fasting.

摘要

研究了冬眠对金背地松鼠(Citellus lateralis)胰腺胰岛素、胰高血糖素、生长抑素和胰多肽的影响。在冬眠期间,胰腺器官重量降至非冬眠体重的57%。冬眠期间所有四种胰腺激素的含量均显著降低。冬眠期间胰岛素、胰多肽和生长抑素的浓度显著降低,但胰高血糖素的浓度未显著降低。冬眠期间胰高血糖素浓度的维持可能与其在禁食期间的反调节和碳水化合物稳态中的作用有关。

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