Maurer Tilman, Sohns Christian, Deiss Sebastian, Rottner Laura, Wohlmuth Peter, Reißmann Bruno, Heeger Christian H, Lemes Christine, Riedl Johannes, Santoro Francesco, Mathew Shibu, Metzner Andreas, Ouyang Feifan, Kuck Karl-Heinz, Wissner Erik
Department of Cardiology, Asklepios Klinik St. Georg, Lohmühlenstraße 5, 20099, Hamburg, Germany.
Division of Cardiology, University of Illinois at Chicago, Chicago, IL, USA.
J Interv Card Electrophysiol. 2017 Sep;49(3):219-226. doi: 10.1007/s10840-017-0261-7. Epub 2017 Jun 10.
The magnetic navigation system (MNS) has shown to be safe and effective for catheter ablation of atrial fibrillation (AF). However, longer procedure duration as compared to manual catheter ablation may limit its widespread use. This study aimed to assess the impact of the newest generation MNS using an optimized mapping and ablation protocol on the efficacy and safety of remote magnetic catheter (RMC)-guided pulmonary vein isolation (PVI).
This observational study included 52 patients with symptomatic AF who underwent RMC-guided PVI using the second-generation MNS Niobe II (initial 28 patients, group I) or the third-generation MNS Niobe ES in combination with an optimized mapping and ablation protocol (24 patients, group II).
Acute PVI was achieved in 26/28 (93%) patients in group I and 24/24 patients (100%) in group II. Mean procedure time was 263.9 ± 81.9 min in group I and significantly lower in group II (139.7 ± 22.6 min, p < 0.01). Mean fluoroscopy time was 18.8 ± 8.7 min in group I and decreased to 7.9 ± 2.6 in group II (p < 0.01). After a median follow-up of 640.5 days (Q1 460.75; Q3 766.5), 16/24 (67%) patients undergoing RMC-guided PVI in group II remained in stable SR. No periprocedural complications were noted for either group.
Use of the third-generation MNS for RMC-guided PVI is safe, effective, and drastically reduced procedure times.
磁导航系统(MNS)已被证明用于心房颤动(AF)的导管消融是安全有效的。然而,与手动导管消融相比,手术时间较长可能会限制其广泛应用。本研究旨在评估使用优化的标测和消融方案的最新一代MNS对远程磁导管(RMC)引导下肺静脉隔离(PVI)的疗效和安全性的影响。
这项观察性研究纳入了52例有症状AF患者,他们使用第二代MNS Niobe II(最初28例患者,第一组)或第三代MNS Niobe ES结合优化的标测和消融方案进行了RMC引导下的PVI(24例患者,第二组)。
第一组26/28例(93%)患者和第二组24/24例(100%)患者实现了急性PVI。第一组的平均手术时间为263.9±81.9分钟,第二组显著缩短(139.7±22.6分钟,p<0.01)。第一组的平均透视时间为18.8±8.7分钟,第二组降至7.9±2.6分钟(p<0.01)。在中位随访640.5天(第一四分位数460.75;第三四分位数766.5)后,第二组中接受RMC引导下PVI的16/24例(67%)患者维持窦性心律稳定。两组均未观察到围手术期并发症。
使用第三代MNS进行RMC引导下的PVI是安全、有效的,且显著缩短了手术时间。